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How applications of nanotechnology can help treat pancreatic cancer?

Posted by :oliverstone276

There has been a lot of improvement in the studies of cancer medicine and treatment. Despite such advancement, pancreatic cancer holds the fourth most popular reason for deaths in western countries. Pancreatic cancer is a complex disease with complicated tumor growth. Nanotechnology in medicine has given us many things answers to complicated diseases. Applications of nanotechnology are showing promising research which can help detect, analyze and make drugs that can be delivered to the affected spot.

Nanotechnology-pancreatic-CancerCarcinoma which grows in the pancreas is very deadly, it is normally detected in advanced stages, they a have good resistant power against any cancer therapy. The risk of damaging normal tissues while applying cure therapies become high, and the challenge remains to find out effective therapies of high doses which will have a clear impact on the tumor cells without affecting the normal cells. Applications of nanotechnology in medicine are showing positive results in curing pancreatic cancer or its early level detection.

Nanodevices to target pancreas cancer cell

Nanotechnology applications not only concentrates on biological science, but involves other science streams such as chemistry, physics or engineering to make an application. To fight pancreatic cancer, scientists have developed nanodevices that can deliver high doses of therapeutic drugs to the targeted cancer cells without affecting the surrounding normal cells. These nanodevices will deliver drugs into the tumor through the angiogenic microvasculature leak in solid tumors with the help of the peptide targeting agent which easily sticks to the pancreatic cancer cells.

Researchers have said that using this nanotechnology in medicine is totally safe. The devices are tested thoroughly. The results show their high efficiency of carrying and delivering highly active chemotherapeutic drugs to the pancreatic cell. The nanodevices helps in imaging, so that the doctors can trace the route of the device where it is travelling and get a live feed from it. The ability of the nanodevices can be measured with the function like imaging and quantitative biodistribution studies. It will help the nanotechnology application to develop and work out the flaws to help cure pancreatic cancer.

Blood tests to detect pancreatic cancer

Two Indianapolis scientist Dr. Murray Korc and Dr. Rajesh Sardar has made a nanosensor which can help detect pancreatic cancer markers in blood samples. They believe the future detection of cancer will become much easier with just a simple blood test. This nanotechnology in medicine can bring a revolution not just detecting pancreatic cancer, but every type of cancer.

Pancreatic cancer is regarded as the most deadliest type of cancer as it is mostly detected in the last or advanced stage when it is nearly impossible to treat the cancer. Only people who were detected with pancreatic cancer at an early stage were able to respond to chemotherapy and medicines.

At present a series of test are done to diagnose any signs of cancer, but Dr. Murray Korc and Dr. Rajesh Sardar are experimenting with micro sensor which can detect cancer cells in blood samples. The sensor can mark the micro RNA, which indicates the growth of pancreatic cancer. It will help to reduce the price of diagnosing and also early detection will give the opportunity to start early treatment.

We’ve actually been meeting almost every Saturday – probably for 18 months now? A long time," Korc said. "And the initial test design was – well, may it works, maybe it doesn’t. But as we worked on improving the technology – it definitely does work. Not only does it work – it actually measures it better than any other test that is currently available.”

The rate of survival is very low or almost nil in case of pancreatic cancer. A person lives about six months after diagnosis, which can improve to a great extent if an early detection can take place.

Only 40 percent of patients survive five years or longer if the cancer is diagnosed at its earliest stage, called "1A, but 1A still isn’t good enough. What we are working toward is finding markers for pre-1A,” he said.

The micro sensor if dropped in the blood sample containing RNA of pancreatic cancer will react instantly. The process is surprisingly inexpensive.

Tag(s) : cancer treatment nanotechnology, nanotechnology in cancer research, treat pancreatic cancer nanotech,    

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